Conversation Starters | ZYNTEGLO™ (betibeglogene autotemcel)

Thinking about ZYNTEGLO

For your consideration:

What would ZYNTEGLO offer me as a treatment?
How long is the ZYNTEGLO treatment journey from start to finish?

For your doctor’s consideration:

What safety considerations should I know about ZYNTEGLO?
Am I a candidate for ZYNTEGLO?
How do you think ZYNTEGLO could change my experience with beta-thalassemia?
What are the possible side effects of treatment with ZYNTEGLO?
How will I receive ZYNTEGLO?
What should I avoid after receiving ZYNTEGLO?

If you are the caregiver, ask your loved one:

How do you think ZYNTEGLO could help you reach your goals?
How do you think ZYNTEGLO could change your relationship with beta-thalassemia?
Do you have any concerns about ZYNTEGLO that we should discuss with the doctor?

Receiving treatment with
ZYNTEGLO gene therapy

For your doctor’s consideration:

Where will I need to go for my treatment with ZYNTEGLO?
Who will be the doctor and care team overseeing my ZYNTEGLO treatment?
What kind of support does the QTC provide to people receiving treatment with ZYNTEGLO?
What might my calendar of events for each step of treatment look like at the QTC?
Where will I be monitored after ZYNTEGLO, and for how long?
What travel and logistics will I need to address before I receive care at the QTC?
What is apheresis like? Mobilization? Chemotherapy?
What can you tell me about the other medicines that I’ll be taking as part of treatment with ZYNTEGLO? What side effects could I expect from these other medicines?
What does follow-up care look like?

Understanding the
ZYNTEGLO Clinical Results

For your consideration:

What specific treatment results are most important to me?
What does the potential efficacy of ZYNTEGLO mean for me?

For your doctor’s consideration:

How will I manage my iron levels after ZYNTEGLO?
Will I still need chelation therapy after ZYNTEGLO?
How long will ZYNTEGLO work and who will monitor my follow-up?

If you are the caregiver, ask your loved one:

What may I want to consider before deciding if ZYNTEGLO is right for my child?

Thinking about ZYNTEGLO

For your consideration:

What would ZYNTEGLO offer me as a treatment?
How long is the ZYNTEGLO treatment journey from start to finish?

For your doctor’s consideration:

What safety considerations should I know about ZYNTEGLO?
Am I a candidate for ZYNTEGLO?
How do you think ZYNTEGLO could change my experience with beta-thalassemia?
What are the possible side effects of treatment with ZYNTEGLO?
How will I receive ZYNTEGLO?
What should I avoid after receiving ZYNTEGLO?

If you are the caregiver, ask your loved one:

How do you think ZYNTEGLO could help you reach your goals?
How do you think ZYNTEGLO could change your relationship with beta-thalassemia?
Do you have any concerns about ZYNTEGLO that we should discuss with the doctor?

Learning about how ZYNTEGLO works

For your consideration:

What does gene therapy with ZYNTEGLO mean for me?

Receiving treatment with ZYNTEGLO gene therapy

For your doctor’s consideration:

Where will I need to go for my treatment with ZYNTEGLO?
Who will be the doctor and care team overseeing my ZYNTEGLO treatment?
What kind of support does the QTC provide to people receiving treatment with ZYNTEGLO?
What might my calendar of events for each step of treatment look like at the QTC?
Where will I be monitored after ZYNTEGLO, and for how long?
What travel and logistics will I need to address before I receive care at the QTC?
What is apheresis like? Mobilization? Chemotherapy?
What can you tell me about the other medicines that I’ll be taking as part of treatment with ZYNTEGLO? What side effects could I expect from these other medicines?
What does follow-up care look like?

Understanding the ZYNTEGLO Clinical Results

For your consideration:

What specific treatment results are most important to me?
What does the potential efficacy of ZYNTEGLO mean for me?

For your doctor’s consideration:

How will I manage my iron levels after ZYNTEGLO?
Will I still need chelation therapy after ZYNTEGLO?
How long will ZYNTEGLO work and who will monitor my follow-up?

If you are the caregiver, ask your loved one:

What may I want to consider before deciding if ZYNTEGLO is right for my child?

Considering coverage for ZYNTEGLO

For your consideration:

What will be covered by my insurance provider?
How much will I be responsible for?
What other assistance could be available for covering ZYNTEGLO?

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